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Glucocorticoids Distinctively Modulate the CFTR Channel with Possible Implications in Lung Development and Transition into Extrauterine Life
During fetal development, the lung is filled with fluid that is secreted by an active Cl- transport promoting lung growth. The basolateral Na(+),K(+),2Cl(-) cotransporter (NKCC1) participates in Cl(-) secretion. The apical Cl(-) channels responsible for secretion are unknown but studies suggest an i...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409322/ https://www.ncbi.nlm.nih.gov/pubmed/25910246 http://dx.doi.org/10.1371/journal.pone.0124833 |