Immucillins Impair Leishmania (L.) infantum chagasi and Leishmania (L.) amazonensis Multiplication In Vitro

Chemotherapy against visceral leishmaniasis is associated with high toxicity and drug resistance. Leishmania parasites are purine auxotrophs that obtain their purines from exogenous sources. Nucleoside hydrolases release purines from nucleosides and are drug targets for anti-leishmanial drugs, absen...

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Detalles Bibliográficos
Autores principales: Freitas, Elisangela Oliveira, Nico, Dirlei, Guan, Rong, Meyer-Fernandes, José Roberto, Clinch, Keith, Evans, Gary B., Tyler, Peter C., Schramm, Vern L., Palatnik-de-Sousa, Clarisa B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409337/
https://www.ncbi.nlm.nih.gov/pubmed/25909893
http://dx.doi.org/10.1371/journal.pone.0124183

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409337/
https://www.ncbi.nlm.nih.gov/pubmed/25909893
http://dx.doi.org/10.1371/journal.pone.0124183

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