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The Unrecognized Effects of Phosphodiesterase 4 on Epithelial Cells in Pulmonary Inflammation

Acute pulmonary inflammation is characterized by migration of polymorphonuclear neutrophils (PMNs) into the different compartments of the lung, passing an endothelial and epithelial barrier. Recent studies showed evidence that phosphodiesterase (PDE)4-inhibitors stabilized endothelial cells. PDE4B a...

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Detalles Bibliográficos
Autores principales: Konrad, Franziska M., Bury, Annette, Schick, Martin A., Ngamsri, Kristian-Christos, Reutershan, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409344/
https://www.ncbi.nlm.nih.gov/pubmed/25909327
http://dx.doi.org/10.1371/journal.pone.0121725