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Functional Validation of a Constitutive Autonomous Silencer Element

Sequences of the genome that are capable of silencing gene expression are thought to play a key role in gene regulation. However, very few silencer elements capable of functioning in mammalian cells have been described, and only a fraction of these have been tested for the ability to function in an...

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Detalles Bibliográficos
Autores principales: Qi, Heyuan, Liu, Mingdong, Emery, David W., Stamatoyannopoulos, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409358/
https://www.ncbi.nlm.nih.gov/pubmed/25910277
http://dx.doi.org/10.1371/journal.pone.0124588