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Chloroform-Methanol Residue of Coxiella burnetii Markedly Potentiated the Specific Immunoprotection Elicited by a Recombinant Protein Fragment rOmpB-4 Derived from Outer Membrane Protein B of Rickettsia rickettsii in C3H/HeN Mice

The obligate intracellular bacteria, Rickettsia rickettsii and Coxiella burnetii, are the potential agents of bio-warfare/bio-terrorism. Here C3H/HeN mice were immunized with a recombinant protein fragment rOmp-4 derived from outer membrane protein B, a major protective antigen of R. rickettsii, com...

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Detalles Bibliográficos
Autores principales: Gong, Wenping, Wang, Pengcheng, Xiong, Xiaolu, Jiao, Jun, Yang, Xiaomei, Wen, Bohai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409375/
https://www.ncbi.nlm.nih.gov/pubmed/25909586
http://dx.doi.org/10.1371/journal.pone.0124664