Activation of the Liver X Receptor by Agonist TO901317 Improves Hepatic Insulin Resistance via Suppressing Reactive Oxygen Species and JNK Pathway

Activation of Liver X receptors (LXRs), key transcriptional regulators of glucose metabolism, normalizes glycemia and improves insulin sensitivity in rodent models with insulin resistance. However, the molecular mechanism is unclear. This study is aimed to elucidate the mechanism of LXRs-mediated li...

Descripción completa

Detalles Bibliográficos
Autores principales: Dong, Ying, Gao, Guirong, Fan, Hongyan, Li, Shengxian, Li, Xuhang, Liu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409387/
https://www.ncbi.nlm.nih.gov/pubmed/25909991
http://dx.doi.org/10.1371/journal.pone.0124778

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409387/
https://www.ncbi.nlm.nih.gov/pubmed/25909991
http://dx.doi.org/10.1371/journal.pone.0124778

Ejemplares similares