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Cell, Isoform, and Environment Factors Shape Gradients and Modulate Chemotaxis

Chemokine gradient formation requires multiple processes that include ligand secretion and diffusion, receptor binding and internalization, and immobilization of ligand to surfaces. To understand how these events dynamically shape gradients and influence ensuing cell chemotaxis, we built a multi-sca...

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Detalles Bibliográficos
Autores principales: Chang, S. Laura, Cavnar, Stephen P., Takayama, Shuichi, Luker, Gary D., Linderman, Jennifer J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409393/
https://www.ncbi.nlm.nih.gov/pubmed/25909600
http://dx.doi.org/10.1371/journal.pone.0123450