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Cell, Isoform, and Environment Factors Shape Gradients and Modulate Chemotaxis
Chemokine gradient formation requires multiple processes that include ligand secretion and diffusion, receptor binding and internalization, and immobilization of ligand to surfaces. To understand how these events dynamically shape gradients and influence ensuing cell chemotaxis, we built a multi-sca...
Autores principales: | Chang, S. Laura, Cavnar, Stephen P., Takayama, Shuichi, Luker, Gary D., Linderman, Jennifer J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409393/ https://www.ncbi.nlm.nih.gov/pubmed/25909600 http://dx.doi.org/10.1371/journal.pone.0123450 |
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