Mitochondrial DNA Stress Primes the Antiviral Innate Immune Response

Mitochondrial DNA (mtDNA) is normally present at thousands of copies per cell and is packaged into several hundred higher-order structures termed nucleoids(1). The abundant mtDNA-binding protein, transcription factor A mitochondrial (TFAM), regulates nucleoid architecture, abundance, and segregation...

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Detalles Bibliográficos
Autores principales: West, A. Phillip, Khoury-Hanold, William, Staron, Matthew, Tal, Michal C., Pineda, Cristiana M., Lang, Sabine M., Bestwick, Megan, Duguay, Brett A., Raimundo, Nuno, MacDuff, Donna A., Kaech, Susan M., Smiley, James R., Means, Robert E., Iwasaki, Akiko, Shadel, Gerald S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409480/
https://www.ncbi.nlm.nih.gov/pubmed/25642965
http://dx.doi.org/10.1038/nature14156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409480/
https://www.ncbi.nlm.nih.gov/pubmed/25642965
http://dx.doi.org/10.1038/nature14156

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