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Adenoviral-Mediated Imaging of Gene Transfer Using a Somatostatin Receptor-Cytosine Deaminase Fusion Protein

Suicide gene therapy is a process by which cells are administered a gene that encodes a protein capable of converting a nontoxic prodrug into an active toxin. Cytosine deaminase (CD) has been widely investigated as a means of suicide gene therapy due to the enzyme’s ability to convert the prodrug 5-...

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Detalles Bibliográficos
Autores principales: Lears, Kimberly A., Parry, Jesse J., Andrews, Rebecca, Nguyen, Kim, Wadas, Thaddeus J., Rogers, Buck E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409539/
https://www.ncbi.nlm.nih.gov/pubmed/25837665
http://dx.doi.org/10.1038/cgt.2015.14