Cargando…
Adenoviral-Mediated Imaging of Gene Transfer Using a Somatostatin Receptor-Cytosine Deaminase Fusion Protein
Suicide gene therapy is a process by which cells are administered a gene that encodes a protein capable of converting a nontoxic prodrug into an active toxin. Cytosine deaminase (CD) has been widely investigated as a means of suicide gene therapy due to the enzyme’s ability to convert the prodrug 5-...
Autores principales: | Lears, Kimberly A., Parry, Jesse J., Andrews, Rebecca, Nguyen, Kim, Wadas, Thaddeus J., Rogers, Buck E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409539/ https://www.ncbi.nlm.nih.gov/pubmed/25837665 http://dx.doi.org/10.1038/cgt.2015.14 |
Ejemplares similares
-
Dose of Adenoviral Vectors Expressing Interleukin‐2 Plays an Important Role in Combined Gene Therapy with Cytosine Deaminase/5–Fluorocytosine: Preclinical Consideration
por: Nakamori, Mikihito, et al.
Publicado: (2002) -
Gene Therapy with Cytosine Deaminase and Endostatin Fusion Gene Mediated by Endothelial Progenitor Cells in Hepatomas
por: Zhang, Yue-Lin, et al.
Publicado: (2020) -
AID/APOBEC cytosine deaminase induces genome-wide kataegis
por: Lada, Artem G, et al.
Publicado: (2012) -
The DNA damage induced by the Cytosine Deaminase APOBEC3A Leads to the production of ROS
por: Niocel, Mathilde, et al.
Publicado: (2019) -
AID/APOBEC deaminases disfavor modified cytosines implicated in DNA demethylation
por: Nabel, Christopher S., et al.
Publicado: (2012)