Altered PPP2R2A and Cyclin D1 expression defines a subgroup of aggressive luminal-like breast cancer

BACKGROUND: PPP2R2A deletions were recently linked to a subgroup of luminal breast carcinoma (BC) that exhibits poor survival. This subgroup also exhibited amplification of a chromosome region containing the Cyclin D1 coding gene, CCND1. Therefore, we aimed to investigate whether a combination of PP...

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Detalles Bibliográficos
Autores principales: Beca, Francisco, Pereira, Miguel, Cameselle-Teijeiro, Jorge F, Martins, Diana, Schmitt, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409761/
https://www.ncbi.nlm.nih.gov/pubmed/25879784
http://dx.doi.org/10.1186/s12885-015-1266-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409761/
https://www.ncbi.nlm.nih.gov/pubmed/25879784
http://dx.doi.org/10.1186/s12885-015-1266-1

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