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Albumin nanoparticles increase the anticancer efficacy of albendazole in ovarian cancer xenograft model

BACKGROUND: The poor prognosis of patients with drug resistant ovarian cancer and the lack of targeted therapy have raised the need for alternative treatments. Albendazole (ABZ) is an anti-parasite compound capable of impairing microtubule formation. We hypothesized that ABZ could be repurposed as a...

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Detalles Bibliográficos
Autores principales: Noorani, Lubna, Stenzel, Martina, Liang, Roger, Pourgholami, Mohammad H, Morris, David L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409778/
https://www.ncbi.nlm.nih.gov/pubmed/25890381
http://dx.doi.org/10.1186/s12951-015-0082-8