Cargando…

Albumin nanoparticles increase the anticancer efficacy of albendazole in ovarian cancer xenograft model

BACKGROUND: The poor prognosis of patients with drug resistant ovarian cancer and the lack of targeted therapy have raised the need for alternative treatments. Albendazole (ABZ) is an anti-parasite compound capable of impairing microtubule formation. We hypothesized that ABZ could be repurposed as a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Noorani, Lubna, Stenzel, Martina, Liang, Roger, Pourgholami, Mohammad H, Morris, David L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409778/ https://www.ncbi.nlm.nih.gov/pubmed/25890381 http://dx.doi.org/10.1186/s12951-015-0082-8

Ejemplares similares

Potent inhibition of tumoral hypoxia-inducible factor 1α by albendazole
por: Pourgholami, Mohammad H, et al.
Publicado: (2010)

Nephrotoxicity of Albendazole and Albendazole Loaded Solid Lipid Nanoparticles in Mice with Experimental Hydatidosis
por: Kohansal, Kobra, et al.
Publicado: (2022)

Evaluation of the Protoscolicidal Effects of Albendazole and Albendazole Loaded Solid Lipid Nanoparticles
por: AMINPOUR, Shohreh, et al.
Publicado: (2019)

Albendazole repurposing on VEGFR-2 for possible anticancer application: In-silico analysis
por: Gaikwad, Nikita Maruti, et al.
Publicado: (2023)

Sub-lethal doses of albendazole induce drug metabolizing enzymes and increase albendazole deactivation in Haemonchus contortus adults
por: Kellerová, Pavlína, et al.
Publicado: (2020)

Efficacy and reinfection with soil-transmitted helminths 18-weeks post-treatment with albendazole-ivermectin, albendazole-mebendazole, albendazole-oxantel pamoate and mebendazole
por: Speich, Benjamin, et al.
Publicado: (2016)

Albumin binding and anticancer effect of magnesium oxide nanoparticles
por: Behzadi, Elham, et al.
Publicado: (2018)

Efficacy of Preoperative Albendazole on Protoscoleces Viability in Hydatid Cyst of the Liver
por: Vahidirad, Ali, et al.
Publicado: (2022)

Exploring the Preparation of Albendazole-Loaded Chitosan-Tripolyphosphate Nanoparticles
por: Kang, Bong-Seok, et al.
Publicado: (2015)

Efficacy and Safety of Nitazoxanide, Albendazole, and Nitazoxanide-Albendazole against Trichuris trichiura Infection: A Randomized Controlled Trial
por: Speich, Benjamin, et al.
Publicado: (2012)

Enhancing the efficacy of albendazole for liver cancer treatment using mesoporous silica nanoparticles: an in vitro study
por: Ghaferi, Mohsen, et al.
Publicado: (2022)

Significance of vascular endothelial growth factor in growth and peritoneal dissemination of ovarian cancer
por: Masoumi Moghaddam, Samar, et al.
Publicado: (2011)

Albumin binding, anticancer and antibacterial properties of synthesized zero valent iron nanoparticles
por: Anbouhi, Tabassom Sedaghat, et al.
Publicado: (2018)

Efficacy of Albendazole and Mebendazole With or Without Levamisole for Ascariasis and Trichuriasis
por: Anto, Endy Juli, et al.
Publicado: (2019)

Utility of Vascular Endothelial Growth Factor Inhibitors in the Treatment of Ovarian Cancer: From Concept to Application
por: Amini, Afshin, et al.
Publicado: (2012)

Pharmacokinetics of Moxidectin combined with Albendazole or Albendazole plus Diethylcarbamazine for Bancroftian Filariasis
por: Chhonker, Yashpal S., et al.
Publicado: (2023)

Improved anticancer delivery of paclitaxel by albumin surface modification of PLGA nanoparticles
por: Esfandyari-Manesh, Mehdi, et al.
Publicado: (2015)

Minocycline Suppresses Interleukine-6, Its Receptor System and Signaling Pathways and Impairs Migration, Invasion and Adhesion Capacity of Ovarian Cancer Cells: In Vitro and In Vivo Studies
por: Ataie-Kachoie, Parvin, et al.
Publicado: (2013)

Reduced efficacy of albendazole against Ascaris lumbricoides in Rwandan schoolchildren
por: Krücken, Jürgen, et al.
Publicado: (2017)

Effect of Albendazole on Human Hydatid Cysts: An Ultrastructural Study
por: Richards, K. Sylvia, et al.
Publicado: (1990)

Comparison of Doxycycline, Minocycline, Doxycycline plus Albendazole and Albendazole Alone in Their Efficacy against Onchocerciasis in a Randomized, Open-Label, Pilot Trial
por: Klarmann-Schulz, Ute, et al.
Publicado: (2017)

Efficacy of Albendazole-Pyrantel Pamoate Compared to Albendazole Alone for Trichuris trichiura Infection in Children: A Double Blind Randomised Controlled Trial
por: Sapulete, Eva Jacomina Jemima, et al.
Publicado: (2020)

Anticancer Efficacy of Cordyceps militaris Ethanol Extract in a Xenografted Leukemia Model
por: Park, Jae Gwang, et al.
Publicado: (2017)

Thiophene Derivatives as Anticancer Agents and Their Delivery to Tumor Cells Using Albumin Nanoparticles
por: Cai, Guangsheng, et al.
Publicado: (2019)

A Cell-Based Screen Reveals that the Albendazole Metabolite, Albendazole Sulfone, Targets Wolbachia
por: Serbus, Laura R., et al.
Publicado: (2012)

Efficacy and safety of moxidectin and albendazole compared to ivermectin and albendazole co-administration in adolescents infected with Trichuris trichiura: a randomized controlled trial protocol
por: Welsche, Sophie, et al.
Publicado: (2021)

Combination Therapy with Doxorubicin-Loaded Reduced Albumin Nanoparticles and Focused Ultrasound in Mouse Breast Cancer Xenografts
por: Kim, Daehyun, et al.
Publicado: (2020)

Efficacy of Albendazole-Chitosan Microsphere-based Treatment for Alveolar Echinococcosis in Mice
por: Abulaihaiti, Maitiseyiti, et al.
Publicado: (2015)

Efficacy of High-Dose Albendazole with Ivermectin for Treating Imported Loiasis, Italy
por: Gobbi, Federico, et al.
Publicado: (2019)

Efficacy of triple dose albendazole treatment for soil-transmitted helminth infections
por: Tee, Mian Zi, et al.
Publicado: (2022)

A Retrospective Study of the Efficacy of Albendazole and Diethylcarbamazine for the Treatment of Human Toxocariasis
por: Magnaval, Jean-François, et al.
Publicado: (2022)

The Use of Cyclodextrin Inclusion Complexes to Increase the Solubility and Pharmacokinetic Profile of Albendazole
por: Ding, Yili, et al.
Publicado: (2023)

Solid Polymeric Nanoparticles of Albendazole: Synthesis, Physico-Chemical Characterization and Biological Activity
por: Racoviceanu, Roxana, et al.
Publicado: (2020)

Albendazole-induced anagen effluvium
por: Ghias, Mondana H., et al.
Publicado: (2019)

Radiolabeled liposome imaging determines an indication for liposomal anticancer agent in ovarian cancer mouse xenograft models
por: Ito, Ken, et al.
Publicado: (2015)

Initial Report on Differential Expression of Sprouty Proteins 1 and 2 in Human Epithelial Ovarian Cancer Cell Lines
por: Moghaddam, Samar Masoumi, et al.
Publicado: (2012)

Nanocrystal Suspensions for Enhancing the Oral Absorption of Albendazole
por: Liang, Zhiwei, et al.
Publicado: (2022)

The Identification of Metabolites and Effects of Albendazole in Alfalfa (Medicago sativa)
por: Raisová Stuchlíková, Lucie, et al.
Publicado: (2020)

Efficacy and Safety of Human Serum Albumin–Cisplatin Complex in U87MG Xenograft Mouse Models
por: Park, Cho Rong, et al.
Publicado: (2020)

An open label, randomized clinical trial to compare the tolerability and efficacy of ivermectin plus diethylcarbamazine and albendazole vs. diethylcarbamazine plus albendazole for treatment of brugian filariasis in Indonesia
por: Supali, Taniawati, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_lhdnob5uodsme2usr7e83nl0tr