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Sleep-like behavior and 24-h rhythm disruption in the Tc1 mouse model of Down syndrome

Down syndrome is a common disorder associated with intellectual disability in humans. Among a variety of severe health problems, patients with Down syndrome exhibit disrupted sleep and abnormal 24-h rest/activity patterns. The transchromosomic mouse model of Down syndrome, Tc1, is a trans-species mo...

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Detalles Bibliográficos
Autores principales: Heise, I, Fisher, S P, Banks, G T, Wells, S, Peirson, S N, Foster, R G, Nolan, P M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409853/
https://www.ncbi.nlm.nih.gov/pubmed/25558895
http://dx.doi.org/10.1111/gbb.12198