LPS exacerbates functional and inflammatory responses to ovalbumin and decreases sensitivity to inhaled fluticasone propionate in a guinea pig model of asthma

BACKGROUND AND PURPOSE: Asthma exacerbations contribute to corticosteroid insensitivity. LPS is ubiquitous in the environment. It causes bronchoconstriction and airway inflammation and may therefore exacerbate allergen responses. This study examined whether LPS and ovalbumin co-administration could...

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Detalles Bibliográficos
Autores principales: Lowe, A P P, Thomas, R S, Nials, A T, Kidd, E J, Broadley, K J, Ford, W R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409909/
https://www.ncbi.nlm.nih.gov/pubmed/25586266
http://dx.doi.org/10.1111/bph.13080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409909/
https://www.ncbi.nlm.nih.gov/pubmed/25586266
http://dx.doi.org/10.1111/bph.13080

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