SomInaClust: detection of cancer genes based on somatic mutation patterns of inactivation and clustering

BACKGROUND: With the advances in high throughput technologies, increasing amounts of cancer somatic mutation data are being generated and made available. Only a small number of (driver) mutations occur in driver genes and are responsible for carcinogenesis, while the majority of (passenger) mutation...

Descripción completa

Detalles Bibliográficos
Autores principales: Van den Eynden, Jimmy, Fierro, Ana Carolina, Verbeke, Lieven PC, Marchal, Kathleen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410004/
https://www.ncbi.nlm.nih.gov/pubmed/25903787
http://dx.doi.org/10.1186/s12859-015-0555-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410004/
https://www.ncbi.nlm.nih.gov/pubmed/25903787
http://dx.doi.org/10.1186/s12859-015-0555-7

Ejemplares similares