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4-Nitro-3-phenylphenol has both androgenic and anti-androgenic-like effects in rats

To investigate the effect of endocrine disruption of 4-nitro-3-phenylphenol (PNMPP) on immature male Wistar-Imamichi rats, the rat pituitary was exposed to PNMPP (10(–5)–10(–9) M) for 24 h with or without gonadotropin-releasing hormone (GnRH) in experiment I. In addition, the Leydig cells (10(–5)–10...

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Detalles Bibliográficos
Autores principales: TRISOMBOON, Jiratthiya, LI, ChunMei, SUZUKI, Akira, WATANABE, Gen, TAYA, Kazuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Society for Reproduction and Development 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410311/
https://www.ncbi.nlm.nih.gov/pubmed/25736398
http://dx.doi.org/10.1262/jrd.2014-110