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A unique chromatin complex occupies young α-satellite arrays of human centromeres

The intractability of homogeneous α-satellite arrays has impeded understanding of human centromeres. Artificial centromeres are produced from higher-order repeats (HORs) present at centromere edges, although the exact sequences and chromatin conformations of centromere cores remain unknown. We use h...

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Detalles Bibliográficos
Autores principales: Henikoff, Jorja G., Thakur, Jitendra, Kasinathan, Sivakanthan, Henikoff, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410388/
https://www.ncbi.nlm.nih.gov/pubmed/25927077
http://dx.doi.org/10.1126/sciadv.1400234