Direct neuronal glucose uptake heralds activity-dependent increases in cerebral metabolism

Metabolically, the brain is a highly active organ that relies almost exclusively on glucose as its energy source. According to the astrocyte-to-neuron lactate shuttle hypothesis, glucose is taken up by astrocytes and converted to lactate, which is then oxidized by neurons. Here we show, using 2-phot...

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Detalles Bibliográficos
Autores principales: Lundgaard, Iben, Li, Baoman, Xie, Lulu, Kang, Hongyi, Sanggaard, Simon, Haswell, John Douglas R, Sun, Wei, Goldman, Siri, Blekot, Solomiya, Nielsen, Michael, Takano, Takahiro, Deane, Rashid, Nedergaard, Maiken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410436/
https://www.ncbi.nlm.nih.gov/pubmed/25904018
http://dx.doi.org/10.1038/ncomms7807

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410436/
https://www.ncbi.nlm.nih.gov/pubmed/25904018
http://dx.doi.org/10.1038/ncomms7807

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