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Direct neuronal glucose uptake heralds activity-dependent increases in cerebral metabolism
Metabolically, the brain is a highly active organ that relies almost exclusively on glucose as its energy source. According to the astrocyte-to-neuron lactate shuttle hypothesis, glucose is taken up by astrocytes and converted to lactate, which is then oxidized by neurons. Here we show, using 2-phot...
Autores principales: | Lundgaard, Iben, Li, Baoman, Xie, Lulu, Kang, Hongyi, Sanggaard, Simon, Haswell, John Douglas R, Sun, Wei, Goldman, Siri, Blekot, Solomiya, Nielsen, Michael, Takano, Takahiro, Deane, Rashid, Nedergaard, Maiken |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410436/ https://www.ncbi.nlm.nih.gov/pubmed/25904018 http://dx.doi.org/10.1038/ncomms7807 |
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