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Permutation-based variance component test in generalized linear mixed model with application to multilocus genetic association study

BACKGROUND: In many medical studies the likelihood ratio test (LRT) has been widely applied to examine whether the random effects variance component is zero within the mixed effects models framework; whereas little work about likelihood-ratio based variance component test has been done in the genera...

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Detalles Bibliográficos
Autores principales: Zeng, Ping, Zhao, Yang, Li, Hongliang, Wang, Ting, Chen, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410500/
https://www.ncbi.nlm.nih.gov/pubmed/25897803
http://dx.doi.org/10.1186/s12874-015-0030-1