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Permutation-based variance component test in generalized linear mixed model with application to multilocus genetic association study
BACKGROUND: In many medical studies the likelihood ratio test (LRT) has been widely applied to examine whether the random effects variance component is zero within the mixed effects models framework; whereas little work about likelihood-ratio based variance component test has been done in the genera...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410500/ https://www.ncbi.nlm.nih.gov/pubmed/25897803 http://dx.doi.org/10.1186/s12874-015-0030-1 |