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Chitosan Prevents Gentamicin-Induced Nephrotoxicity via a Carbonyl Stress-Dependent Pathway

Aminoglycosides are widely used to treat infections; however, their applications are limited by nephrotoxicity. With the increase of antibiotic resistance, the use of aminoglycosides is inevitable. Low-molecular-weight chitosan (LMWC) has shown renal protective effects in dialysis patients. However,...

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Detalles Bibliográficos
Autores principales: Chou, Chu-Kung, Li, Yi-Chieh, Chen, Shih-Ming, Shih, Yi-Min, Lee, Jen-Ai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410504/
https://www.ncbi.nlm.nih.gov/pubmed/25954755
http://dx.doi.org/10.1155/2015/675714