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The desensitization gate of inhibitory Cys-loop receptors

Cys-loop neurotransmitter-gated ion channels are vital for communication throughout the nervous system. Following activation, these receptors enter into a desensitized state in which the ion channel shuts even though the neurotransmitter molecules remain bound. To date, the molecular determinants un...

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Detalles Bibliográficos
Autores principales: Gielen, Marc, Thomas, Philip, Smart, Trevor G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410641/
https://www.ncbi.nlm.nih.gov/pubmed/25891813
http://dx.doi.org/10.1038/ncomms7829