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MicroRNA modules prefer to bind weak and unconventional target sites

Motivation: MicroRNAs (miRNAs) play critical roles in gene regulation. Although it is well known that multiple miRNAs may work as miRNA modules to synergistically regulate common target mRNAs, the understanding of miRNA modules is still in its infancy. Results: We employed the recently generated hig...

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Detalles Bibliográficos
Autores principales: Ding, Jun, Li, Xiaoman, Hu, Haiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410656/
https://www.ncbi.nlm.nih.gov/pubmed/25527098
http://dx.doi.org/10.1093/bioinformatics/btu833