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Integrating alignment-based and alignment-free sequence similarity measures for biological sequence classification

Motivation: Alignment-based sequence similarity searches, while accurate for some type of sequences, can produce incorrect results when used on more divergent but functionally related sequences that have undergone the sequence rearrangements observed in many bacterial and viral genomes. Here, we pro...

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Detalles Bibliográficos
Autores principales: Borozan, Ivan, Watt, Stuart, Ferretti, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410667/
https://www.ncbi.nlm.nih.gov/pubmed/25573913
http://dx.doi.org/10.1093/bioinformatics/btv006