Using isoelectric point to determine the pH for initial protein crystallization trials

Motivation: The identification of suitable conditions for crystallization is a rate-limiting step in protein structure determination. The pH of an experiment is an important parameter and has the potential to be used in data-mining studies to help reduce the number of crystallization trials required...

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Detalles Bibliográficos
Autores principales: Kirkwood, Jobie, Hargreaves, David, O’Keefe, Simon, Wilson, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410668/
https://www.ncbi.nlm.nih.gov/pubmed/25573921
http://dx.doi.org/10.1093/bioinformatics/btv011