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Dynamic caveolae exclude bulk membrane proteins and are required for sorting of excess glycosphingolipids

Caveolae have long been implicated in endocytosis. Recent data question this link, and in the absence of specific cargoes the potential cellular function of caveolar endocytosis remains unclear. Here we develop new tools, including doubly genome-edited cell lines, to assay the subcellular dynamics o...

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Detalles Bibliográficos
Autores principales: Shvets, Elena, Bitsikas, Vassilis, Howard, Gillian, Hansen, Carsten Gram, Nichols, Benjamin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410672/
https://www.ncbi.nlm.nih.gov/pubmed/25897946
http://dx.doi.org/10.1038/ncomms7867