Cell-lineage heterogeneity and driver mutation recurrence in pre-invasive breast neoplasia

BACKGROUND: All cells in an individual are related to one another by a bifurcating lineage tree, in which each node is an ancestral cell that divided into two, each branch connects two nodes, and the root is the zygote. When a somatic mutation occurs in an ancestral cell, all its descendants carry t...

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Detalles Bibliográficos
Autores principales: Weng, Ziming, Spies, Noah, Zhu, Shirley X, Newburger, Daniel E, Kashef-Haghighi, Dorna, Batzoglou, Serafim, Sidow, Arend, West, Robert B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410742/
https://www.ncbi.nlm.nih.gov/pubmed/25918554
http://dx.doi.org/10.1186/s13073-015-0146-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410742/
https://www.ncbi.nlm.nih.gov/pubmed/25918554
http://dx.doi.org/10.1186/s13073-015-0146-2

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