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Sensitization of neonatal rat lumbar motoneuron by the inflammatory pain mediator bradykinin

Bradykinin (Bk) is a potent inflammatory mediator that causes hyperalgesia. The action of Bk on the sensory system is well documented but its effects on motoneurons, the final pathway of the motor system, are unknown. By a combination of patch-clamp recordings and two-photon calcium imaging, we foun...

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Detalles Bibliográficos
Autores principales: Bouhadfane, Mouloud, Kaszás, Attila, Rózsa, Balázs, Harris-Warrick, Ronald M, Vinay, Laurent, Brocard, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410746/
https://www.ncbi.nlm.nih.gov/pubmed/25781633
http://dx.doi.org/10.7554/eLife.06195