Pilot study investigating the prognostic significance of thymidine phosphorylase expression in patients with metastatic breast cancer: a single institution retrospective analysis

BACKGROUND: The thymidine phosphorylase (TP) enzyme is expressed in higher levels in cancer tissue when compared with normal tissue. It is involved in the intratumoral activation of widely prescribed pyrimidine-derived antimetabolites such as 5′-deoxy-5-fluorouridine and capecitabine (Xeloda(®)). Th...

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Detalles Bibliográficos
Autores principales: Tedeschi, Anna Lisa, Eslami, Zohreh, Garoufalis, Evgenia, Saleh, Ramy R, Omeroglu, Atilla, Altinel, Gulbeyaz, Ait-Tihyaty, Maria, Jean-Claude, Bertrand, Mihalcioiu, Catalin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410895/
https://www.ncbi.nlm.nih.gov/pubmed/25960662
http://dx.doi.org/10.2147/OTT.S71089

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410895/
https://www.ncbi.nlm.nih.gov/pubmed/25960662
http://dx.doi.org/10.2147/OTT.S71089

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