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Flow-dependent regulation of genome-wide mRNA and microRNA expression in endothelial cells in vivo

Atherosclerosis preferentially occurs in arterial regions exposed to disturbed blood flow (d-flow), in part, due to alterations in gene expression in the endothelium. While numerous in vitro studies have shown how anti-atherogenic flow and pro-atherogenic flow differently regulate gene expression of...

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Detalles Bibliográficos
Autores principales: Kumar, Sandeep, Kim, Chan Woo, Son, Dong Ju, Ni, Chih Wen, Jo, Hanjoong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411008/
https://www.ncbi.nlm.nih.gov/pubmed/25977794
http://dx.doi.org/10.1038/sdata.2014.39