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12-O-Tetradecanoylphorbol-13-Acetate Induces Up-Regulated Transcription of Variant 1 but Not Variant 2 of VIL2 in Esophageal Squamous Cell Carcinoma Cells via ERK1/2/AP-1/Sp1 Signaling

The membrane-cytoskeleton link organizer ezrin may be the most “dramatic” tumor marker, being strongly over-expressed in nearly one-third of human malignancies. However, the molecular mechanisms of aberrant ezrin expression still need to be clarified. Ezrin, encoded by the VIL2 gene, has two transcr...

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Detalles Bibliográficos
Autores principales: Zhang, Xiao-Dan, Xie, Jian-Jun, Liao, Lian-Di, Long, Lin, Xie, Yang-Min, Li, En-Min, Xu, Li-Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411055/
https://www.ncbi.nlm.nih.gov/pubmed/25915860
http://dx.doi.org/10.1371/journal.pone.0124680