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Evaluating the SERCA2 and VEGF mRNAs as Potential Molecular Biomarkers of the Onset and Progression in Huntington’s Disease

Abnormalities of intracellular Ca(2+) homeostasis and signalling as well as the down-regulation of neurotrophic factors in several areas of the central nervous system and in peripheral tissues are hallmarks of Huntington’s disease (HD). As there is no therapy for this hereditary, neurodegenerative f...

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Detalles Bibliográficos
Autores principales: Cesca, Federica, Bregant, Elisa, Peterlin, Borut, Zadel, Maja, Dubsky de Wittenau, Giorgia, Siciliano, Gabriele, Ceravolo, Roberto, Petrozzi, Lucia, Pauletto, Giada, Verriello, Lorenzo, Bergonzi, Paolo, Damante, Giuseppe, Barillari, Giovanni, Lucci, Bruno, Curcio, Francesco, Lonigro, Incoronata Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411078/
https://www.ncbi.nlm.nih.gov/pubmed/25915065
http://dx.doi.org/10.1371/journal.pone.0125259