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TNFA Haplotype Genetic Testing Improves HLA in Estimating the Risk of Celiac Disease in Children
BACKGROUND: TNF-α and IFN-γ play a role in the development of mucosal damage in celiac disease (CD). Polymorphisms of TNFA and IFNG genes, as well as of the TNFRSF1A gene, encoding the TNF-α receptor 1, might underlie different inter-individual disease susceptibility over a common HLA risk backgroun...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411089/ https://www.ncbi.nlm.nih.gov/pubmed/25915602 http://dx.doi.org/10.1371/journal.pone.0123244 |