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Regulation of L-type Voltage Gated Calcium Channel CACNA1S in Macrophages upon Mycobacterium tuberculosis Infection

We demonstrated earlier the inhibitory role played by Voltage Gated Calcium Channels (VGCCs) in regulating Mycobacterium tuberculosis (M. tb) survival and pathogenesis. In this report, we investigated mechanisms and key players that regulate the surface expression of VGCC-CACNA1S by Rv2463 and M. tb...

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Detalles Bibliográficos
Autores principales: Antony, Cecil, Mehto, Subhash, Tiwari, Brijendra K., Singh, Yogendra, Natarajan, Krishnamurthy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411123/
https://www.ncbi.nlm.nih.gov/pubmed/25915405
http://dx.doi.org/10.1371/journal.pone.0124263