Modified Proofreading PCR for Detection of Point Mutations, Insertions and Deletions Using a ddNTP-Blocked Primer

The development of simple, accurate, rapid and cost-effective technologies for mutation detection is crucial to the early diagnosis and prevention of numerous genetic diseases, pharmacogenetics, and drug resistance. Proofreading PCR (PR-PCR) was developed for mutation detection in 1998 but is rarely...

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Detalles Bibliográficos
Autores principales: Hao, Weiming, Fan, Lujuan, Chen, Qianqian, Chen, Xiaoxiang, Zhang, Sichao, Lan, Ke, Lu, Jian, Zhang, Chiyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411138/
https://www.ncbi.nlm.nih.gov/pubmed/25915410
http://dx.doi.org/10.1371/journal.pone.0123468

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411138/
https://www.ncbi.nlm.nih.gov/pubmed/25915410
http://dx.doi.org/10.1371/journal.pone.0123468

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