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SIRT3 Overexpression Attenuates Palmitate-Induced Pancreatic β-Cell Dysfunction
Abnormally high levels of circulating free fatty acids can lead to pancreatic islet β-cell dysfunction and apoptosis, contributing to β-cell failure in Type 2 diabetes. The NAD(+)-dependent protein deacetylase Sirtuin-3 (SIRT3) has been implicated in Type 2 diabetes. In this study, we tested whether...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411148/ https://www.ncbi.nlm.nih.gov/pubmed/25915406 http://dx.doi.org/10.1371/journal.pone.0124744 |