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SIRT3 Overexpression Attenuates Palmitate-Induced Pancreatic β-Cell Dysfunction

Abnormally high levels of circulating free fatty acids can lead to pancreatic islet β-cell dysfunction and apoptosis, contributing to β-cell failure in Type 2 diabetes. The NAD(+)-dependent protein deacetylase Sirtuin-3 (SIRT3) has been implicated in Type 2 diabetes. In this study, we tested whether...

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Detalles Bibliográficos
Autores principales:	Kim, Min, Lee, Ji Seon, Oh, Joo En, Nan, Jinyan, Lee, Hakmo, Jung, Hye Seung, Chung, Sung Soo, Park, Kyong Soo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411148/ https://www.ncbi.nlm.nih.gov/pubmed/25915406 http://dx.doi.org/10.1371/journal.pone.0124744

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