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A Human Anti-M2 Antibody Mediates Antibody-Dependent Cell-Mediated Cytotoxicity (ADCC) and Cytokine Secretion by Resting and Cytokine-Preactivated Natural Killer (NK) Cells

The highly conserved matrix protein 2 (M2) is a good candidate for the development of a broadly protective influenza vaccine that induces long-lasting immunity. In animal models, natural killer (NK) cells have been proposed to play an important role in the protection provided by M2-based vaccines th...

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Detalles Bibliográficos
Autores principales: Simhadri, Venkateswara R., Dimitrova, Milena, Mariano, John L., Zenarruzabeitia, Olatz, Zhong, Weimin, Ozawa, Tatsuhiko, Muraguchi, Atsushi, Kishi, Hiroyuki, Eichelberger, Maryna C., Borrego, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411161/
https://www.ncbi.nlm.nih.gov/pubmed/25915748
http://dx.doi.org/10.1371/journal.pone.0124677