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Hsp70 in cancer: back to the future

Mechanistic studies from cell culture and animal models have revealed critical roles for the heat shock protein Hsp70 in cancer initiation and progression. Surprisingly, many effects of Hsp70 on cancer have not been related to its chaperone activity, but rather to its role(s) in regulating cell sign...

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Detalles Bibliográficos
Autores principales: Sherman, Michael Y., Gabai, Vladimir L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411196/
https://www.ncbi.nlm.nih.gov/pubmed/25347739
http://dx.doi.org/10.1038/onc.2014.349