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ACK1/TNK2 Tyrosine Kinase: Molecular Signaling and Evolving Role in Cancers

Deregulated tyrosine kinase signaling alters cellular homeostasis to drive cancer progression. The emergence of a non-receptor tyrosine kinase, ACK1 as an oncogenic kinase, has uncovered novel mechanisms by which tyrosine kinase signaling promotes cancer progression. While early studies focused on A...

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Detalles Bibliográficos
Autores principales: Mahajan, Kiran, Mahajan, Nupam P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411206/
https://www.ncbi.nlm.nih.gov/pubmed/25347744
http://dx.doi.org/10.1038/onc.2014.350