The Fabry disease-associated lipid Lyso-Gb3 enhances voltage-gated calcium currents in sensory neurons and causes pain

Fabry disease is an X-linked lysosomal storage disorder characterised by accumulation of glycosphingolipids, and accompanied by clinical manifestations, such as cardiac disorders, renal failure, pain and peripheral neuropathy. Globotriaosylsphingosine (lyso-Gb3), a deacylated form of globotriaosylce...

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Detalles Bibliográficos
Autores principales: Choi, L., Vernon, J., Kopach, O., Minett, M.S., Mills, K., Clayton, P.T., Meert, T., Wood, J.N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Scientific Publishers Ireland 2015
Materias:
Plenary Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411215/
https://www.ncbi.nlm.nih.gov/pubmed/25697597
http://dx.doi.org/10.1016/j.neulet.2015.01.084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411215/
https://www.ncbi.nlm.nih.gov/pubmed/25697597
http://dx.doi.org/10.1016/j.neulet.2015.01.084

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