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Mechanism for phosphoinositide selectivity and activation of TRPV1 ion channels
Although PI(4,5)P(2) is believed to play an essential role in regulating the activity of numerous ion channels and transporters, the mechanisms by which it does so are unknown. Here, we used the ability of the TRPV1 ion channel to discriminate between PI(4,5)P(2) and PI(4)P to localize the region of...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411251/ https://www.ncbi.nlm.nih.gov/pubmed/25918361 http://dx.doi.org/10.1085/jgp.201511354 |