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The yeast ERAD-C ubiquitin ligase Doa10 recognizes an intramembrane degron
Aberrant endoplasmic reticulum (ER) proteins are eliminated by ER-associated degradation (ERAD). This process involves protein retrotranslocation into the cytosol, ubiquitylation, and proteasomal degradation. ERAD substrates are classified into three categories based on the location of their degrada...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411271/ https://www.ncbi.nlm.nih.gov/pubmed/25918226 http://dx.doi.org/10.1083/jcb.201408088 |