The yeast ERAD-C ubiquitin ligase Doa10 recognizes an intramembrane degron

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Aberrant endoplasmic reticulum (ER) proteins are eliminated by ER-associated degradation (ERAD). This process involves protein retrotranslocation into the cytosol, ubiquitylation, and proteasomal degradation. ERAD substrates are classified into three categories based on the location of their degrada...

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Detalles Bibliográficos
Autores principales: Habeck, Gregor, Ebner, Felix A., Shimada-Kreft, Hiroko, Kreft, Stefan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411271/
https://www.ncbi.nlm.nih.gov/pubmed/25918226
http://dx.doi.org/10.1083/jcb.201408088

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