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FOXO1 differentially regulates both normal and diabetic wound healing

Healing is delayed in diabetic wounds. We previously demonstrated that lineage-specific Foxo1 deletion in keratinocytes interfered with normal wound healing and keratinocyte migration. Surprisingly, the same deletion of Foxo1 in diabetic wounds had the opposite effect, significantly improving the he...

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Detalles Bibliográficos
Autores principales: Zhang, Chenying, Ponugoti, Bhaskar, Tian, Chen, Xu, Fanxing, Tarapore, Rohinton, Batres, Angelika, Alsadun, Sarah, Lim, Jason, Dong, Guangyu, Graves, Dana T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411275/
https://www.ncbi.nlm.nih.gov/pubmed/25918228
http://dx.doi.org/10.1083/jcb.201409032