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The source of matrix-degrading enzymes in human cancer: Problems of research reproducibility and possible solutions

Matrix degradation is central to tumor pathogenesis. Enzymes that degrade extracellular matrix are abundant in tumors. But which out of the complex mixture of cells that form a tumor produces them? Surprisingly, several hundred studies devoted to this question have provided confusion rather than cla...

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Detalles Bibliográficos
Autores principales: Madsen, Daniel H., Bugge, Thomas H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411277/
https://www.ncbi.nlm.nih.gov/pubmed/25918222
http://dx.doi.org/10.1083/jcb.201501034