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Extracellular MRP8/14 is a regulator of β2 integrin-dependent neutrophil slow rolling and adhesion

Myeloid-related proteins (MRPs) 8 and 14 are cytosolic proteins secreted from myeloid cells as proinflammatory mediators. Currently, the functional role of circulating extracellular MRP8/14 is unclear. Our present study identifies extracellular MRP8/14 as an autocrine player in the leukocyte adhesio...

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Detalles Bibliográficos
Autores principales: Pruenster, Monika, Kurz, Angela R. M., Chung, Kyoung-Jin, Cao-Ehlker, Xiao, Bieber, Stephanie, Nussbaum, Claudia F., Bierschenk, Susanne, Eggersmann, Tanja K., Rohwedder, Ina, Heinig, Kristina, Immler, Roland, Moser, Markus, Koedel, Uwe, Gran, Sandra, McEver, Rodger P., Vestweber, Dietmar, Verschoor, Admar, Leanderson, Tomas, Chavakis, Triantafyllos, Roth, Johannes, Vogl, Thomas, Sperandio, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411303/
https://www.ncbi.nlm.nih.gov/pubmed/25892652
http://dx.doi.org/10.1038/ncomms7915