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Evolution of the RAG1-RAG2 locus: both proteins came from the same transposon
ABSTRACT: The RAG1 and RAG2 proteins are essential subunits of the V(D)J recombinase that is required for the generation of the enormous variability of antibodies and T-cell receptors in jawed vertebrates. It was demonstrated previously that the 600-aa catalytic core of RAG1 evolved from the transpo...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411706/ https://www.ncbi.nlm.nih.gov/pubmed/25928409 http://dx.doi.org/10.1186/s13062-015-0055-8 |